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SCCS/1596/18 Final Opinion on Colloidal Silver (nano) __________________________________________________________________________________________ 7. ABBREVIATIONS AND GLOSSARY OF TERMS AAS ACGIH ADME AFM AgNPs BET CAS Colipa Colloidal silver DLS ECVAM EDX EFSA FTIR GC/LC-MS ICP-MS In vitro test method IARCC ISO MTT Nanomaterial Nanoparticle NRU NTP OECD SAD pattern SEM SMPS Solubility Systemic effects TDS meter TEM UV-Vis VSSA Atomic absorption spectroscopy American Conference of Governmental Industrial Hygienists Absorption, Distribution, Metabolism, Excretion Atomic force microscopy Silver nanoparticles Brunauer Emmett and Teller method based on nitrogen gas absorption A chemical registry system established by the Chemical Abstracts Service (CAS) European Cosmetics Association (formerly the European Cosmetic Toiletry and Perfumery Association). Now Cosmetics Europe Colloidal dispersion of silver particles in water Dynamic light scattering European Centre for the Validation of Alternative Methods Energy Dispersive X-ray European Food Safety Authority Fourier transform infrared spectroscopy Gas Chromatography/ Liquid Chromatography coupled with Mass Spectrometry Inductively coupled plasma mass spectrometry Biological method that uses organs, tissue sections and tissue cultures, isolated cells and their cultures, cell lines and subcellular fractions, or non-biological method that uses chemical interaction studies, receptor binding studies, etc [Rogiers and Beken 2000] International Agency on Research of Cancer International Organization for Standardization 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide An insoluble or biopersistent and intentionally manufactured material with one or more external dimensions, or an internal structure, on the scale from 1 to 100 nm [Regulation (EC) No 1223/2009] A nano-object with all three external dimensions in the nanoscale [ISO/TS 27687:2008, Nanotechnologies - Terminology and definitions for nano] Neutral Red Uptake cytotoxicity test National Toxicology Program Organisation for Economic Co-operation and Development Selected area diffraction pattern Scanning electron microscopy Scanning mobility particle sizer The terms ‘solubility’ and ‘persistence’ are often used to describe the rate of “degradation”. As such there are a number of definitions of solubility (see SCENIHR Opinion ‘Scientific Basis for the Definition of the Term “Nanomaterial”, 8 December 2010). Solubility in the context of this guidance means disintegration of a nanomaterial in an aqueous medium or biological environment into molecular components with the loss of nano features Systemic effect refers to an adverse health effect that takes place at a location distant from the body's initial point of contact and presupposes absorption has taken place Total dissolved solids meter Transmission electron microscopy Ultraviolet-visible spectrophotometry Volume specific surface area (see Kreyling et al., 2010) 33PDF Image | Consumer Safety SCCS OPINION ON Colloidal Silver (nano)
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