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SCCS/1596/18 Final Opinion on Colloidal Silver (nano) __________________________________________________________________________________________ NB. Only real data provided by the Applicant are mentioned in the Table, statements such as “not provided”, “does not concern” etc. are not included as they give no relevant information for the Opinion. SCCS comment: Data should be provided for the silver nanomaterial in the colloidal silver dispersion and not for the dispersion itself. The boiling point of approx. 100 ̊C or 99.5 ̊C (column 2 and 5 of Table 4) is the boiling temperature of the dispersion’s water content. Additional physicochemical characterisation data should be provided for all the different colloidal silver dispersions. 3.1.9. Particle size and shape Dispersion A, B, C, D, J, K, L: 2-5 nm (80-85%) 5-100 nm (15-20%) Dispersion F, G: Dispersion I: Lowest cut-off = 1.56 nm Number weighted median = 5.79 nm 39 nm Ref: 3, 5, 11, 39, 48 Ref: 16, 19 Ref: 25 A microscopic picture (scanning electron microscopy, SEM) was only provided for colloidal dispersion I. Additional information Figure 1. SEM picture of dispersion I The physical form/shape of the nanoparticle of material A is stated to be spherical. Ref.: 39 Particle size distribution of colloidal silver dispersion A has been determined by means of a JEM 2000EX Transmission Electron Microscopy (TEM) with beam energy of 200 keV and a resolution of 0.3 nm. The microscopic images were taken to determine particle morphology. The particles deposited on the carbon film were single and in clusters. Diameters of the 13 Ref.:26PDF Image | Consumer Safety SCCS OPINION ON Colloidal Silver (nano)
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