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SCCS/1596/18 Final Opinion on Colloidal Silver (nano) __________________________________________________________________________________________ Ref.:55 For dispersion I, additional data on solubility have been provided. The concentration of ionic silver in as-prepared colloidal silver Ag 100 by TDS was measured every 24 hours (for several months). No increase in ionic silver concentration was demonstrated, which allows the manufacturer to consider that colloidal silver Ag 100 is a stable suspension. No “further dissolution” of silver, i.e. Ag0 → AgI in aqueous solution occurs. Ref.: 53 SCCS comment: Information on dissolution rates of the nanomaterial in relevant solvents must be provided for all colloidal silver dispersions. Global statements about solubility not supported by data cannot be accepted. For colloidal silver dispersion A, B, C, D, J, K, L, no experimental data on solubility were submitted. Additional experiments on solubility were only provided for dispersion I. Similarly, the statement “no further dissolution of silver occurs” is not supported by the data provided. 3.1.7. Log Pow: 3.1.8. Partition coefficient (Log Pow) not applicable Additional physical and chemical specifications Table 4: Additional physical and chemical specifications provided by ten Applicants Specification A, B, C, D, J, K, L Ref 5,11,39,42,46 E Ref 13,15 H Ref 22 I Ref 52 Comments column I Melting point Boiling point Viscosity pH Turbidity/Opacity Colour Approx. 100 ̊C 1000 x 10-6 Pa x s (100 ppm) 5-7 (6-7.5) (100 ppm) max 8 NTU max 5 Pt/l 960 ̊C 2212 ̊C 99.5 ̊C 7.33 (at 23.1 ̊C) Determined by thermometer using scale up to 110 ̊C Provided by standard laboratory pH meter Density 0.99-1.01 g/cm3 1.00 kg/l (at 20.0 ̊C) 0.997504 g/cm3 at 24.0 ̊C Determined by a pycnometer Precision level of density in column I is too high 5.5 – 7 (max 0.015%) Conductivity 5.0-50.0 μS/cm 23.07 μS 0.5 μS Tested by conductometer 12PDF Image | Consumer Safety SCCS OPINION ON Colloidal Silver (nano)
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