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US 2005/0142231A1 Jun.30,2005 pharmacological activity experiments show that the com poundproductscanenhancetheactivityofLCATremark ably Whereas the standard control-atromid-S exhibits no remarkable action. This shoWs that the compound products act better than atromid-S (Table 3). TABLE 1-continued Source of raW material and composition of the ?ve-plantcompoundofhypolipemicproducts 3-He’b“Gy'm’emmae Cmmbimme Stern tuber or Whole grass of Gynostema Pentaphyllum (Thunb.)Makino 4. Frucms Ligustri Lucidi Oleaceae Fruit of Ligustmm Lucidum Ait. 5_ Herba Epimedii Berberidaceae Branches and leaves ofEpimedium Brevicomum Maxm. Total [0011] [0010] BRIEF DESCRIPTION OF THE SEVERAL vIEWs OF THE DRAWING 20-83% 20.83% 16_67% 100% TABLE 1 Source of raW material and composition of the ?ve-plant compound of hypolipemic products 1_Rhizoma Alismalis Alismataceae Stern tuber ofAlisma Orientalis (Sam) Juzep. 2.Rhizoma Ourcumae Longae Zingberaceae Stern tuber of Curcumae LongaL. 25% 16.67% Componentsoffive-plant volatile oil Were extracted With supercriticalfluidCO2 extractant CO2 extractantand plantscomposition,Were isolated and rectified Five plant compound raW materials 300 kg Water Was added to every 100 kg of raW materials and extracted at 100° C. for 3 hours FiltrateextractedbyWater I IResidueI 200 kg Water Was added to every 100 kg residue and extracted at 100° C. for 2 hours TABLE 2 Manufacturing Process and Flowchart for the ?ve-plant Compound Hypolipernic Products Filtrate extracted by Water Filtrate extracted by Water Filtrate extracted by Water Was blended Filtrate Was concentrated. 100 kg Water Was added to every 100 kg residue and extracted at 100° C. for 1 hour Residue discarded ILefttostandfor6hoursatroomtemperatureandsupernatantWasdiscarded. I I AbsorbWithWLD resinthroughacolumnfiledWithWLD resin. I IComponentsabsorbedonWLD resinWereelutedWith65%ethanolandethanolWasrecovered. Spry dried at 85° C. Quantitative analysis by fingerprinting Was made Fabrication of standard throughhighperformanceliquidchromatography. productPDF Image | PHARMACEUTICAL ACTIVITY AND MANUFACTURING METHOD
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